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AleisterCrowley wrote:I packed in the real cigarettes a while back, but I still 'vape' so still addicted to nicotine! In fact my nicotine intake has probably increased to 40-a-day levels as I can vape indoors
AleisterCrowley wrote:In large doses it's lethal, in smaller doses ...not sure what the long term effects are, if any
Beyond addiction, both short and long-term nicotine exposure have not been established as dangerous to adults,[19] except among certain vulnerable groups
https://en.wikipedia.org/wiki/Nicotine
Of course 'not been established as' doesn't mean 100% safe , although vastly safer than real smoking
Nicotine increases heart rate and blood pressure[56] and induces abnormal heart rhythms.[57] Nicotine can also induce potentially atherogenic genes in human coronary artery endothelial cells.[58] Microvascular injury can result through its action on nicotinic acetylcholine receptors (nAChRs).[59] Nicotine does not adversely affect serum cholesterol levels,[51] but a 2015 review found it may elevate serum cholesterol levels.[23] Many quitting smoking studies using nicotine medicines report lowered dyslipidemia with considerable benefit in HDL/LDL ratios.[52] Nicotine supports clot formation and aids in plaque formation by enhancing vascular smooth muscle.[23]