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Long covid

The home for all non-political Coronavirus (Covid-19) discussions on The Lemon Fool
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This is the home for all non-political Coronavirus (Covid-19) discussions on The Lemon Fool
88V8
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Re: Long covid

#440150

Postby 88V8 » September 6th, 2021, 7:18 pm

Data from the Zoe Covid symptom study https://covid.joinzoe.com/ has been studied by researchers at King's College.

Data from nearly one million fully vaccinated subjects was analysed in the new research. Compared to unvaccinated controls, the research found vaccinated individuals experiencing a breakthrough COVID-19 infection were 49% less likely to report symptoms lasting longer than 28 days.

Presented in The Lancet https://www.thelancet.com/journals/lani ... 73-3099(21)00460-6/fulltext

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88V8
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Re: Long covid

#440157

Postby 88V8 » September 6th, 2021, 8:00 pm


88V8
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Re: Long covid

#443653

Postby 88V8 » September 19th, 2021, 6:48 pm

US to invest $$$ in long long-covid study.
The US National Institutes of Health said Wednesday it's starting a $470 million study to try to understand what's become known as long Covid—the long-term, sometimes serious effects of Covid-19.
The study will aim to include 30,000-40,000 people and will make use of digital data -- including input from wearable devices, the NIH said. - CNN


https://edition.cnn.com/2021/09/15/health/long-covid-nih-study/index.html

Up to a third of infectees are said to develop long-covid. So whether or not the vaccine prevents serious infection, better not to be infected at all at all.

V8

onthemove
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Re: Long covid

#443663

Postby onthemove » September 19th, 2021, 7:20 pm

88V8 wrote:Up to a third of infectees are said to develop long-covid. So whether or not the vaccine prevents serious infection, better not to be infected at all at all.


"Up to a third" according to who?

The ONS statistics seem to suggest it's only around 1 in 40...

https://www.bbc.co.uk/news/health-58584558

... that's less than 3% of infections rather than 33%

And even then that 1 in 40 might only be a minor case of just 1 or 2 lingering symptoms, not necessarily serious symptoms.

88V8
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Re: Long covid

#443672

Postby 88V8 » September 19th, 2021, 8:15 pm

onthemove wrote:
88V8 wrote:Up to a third of infectees are said to develop long-covid. So whether or not the vaccine prevents serious infection, better not to be infected at all at all.

"Up to a third" according to who?

'Experts' according to the headline of that CNN piece.
Perhaps it's a matter of defining what constitutes 'long'.

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gryffron
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Re: Long covid

#443764

Postby gryffron » September 20th, 2021, 9:54 am

88V8 wrote:
onthemove wrote:"Up to a third" according to who?

'Experts' according to the headline of that CNN piece.
Perhaps it's a matter of defining what constitutes 'long'.

Ah. How to lie with statistics. 3% IS "up to 1/3". :twisted:

To be fair, I suspect you're both right. 1/3 have SOME post infection effects of covid. 3% are serious. A study would want to look at both.

Gryff

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Re: Long covid

#443777

Postby redsturgeon » September 20th, 2021, 10:25 am

A key variable which may account for the differences may be the length of time measured after the diagnosis that symptom persist.

John

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Re: Long covid

#444079

Postby 88V8 » September 21st, 2021, 10:50 am

redsturgeon wrote:A key variable which may account for the differences may be the length of time measured after the diagnosis that symptoms persist.

Or it could be the 'experts' trying to drum up Federal funding.... surely not....

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Re: Long covid

#470561

Postby XFool » January 5th, 2022, 6:29 pm

Could microclots help explain the mystery of long Covid?
Resia Pretorius

The Guardian

My lab has found significant microclot formation in long Covid patients. Unfortunately, these are missed in routine blood tests

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Re: Long covid

#471166

Postby 88V8 » January 7th, 2022, 3:24 pm

XFool wrote:Could microclots help explain the mystery of long Covid?

I have seen covid described as a blood disease that is spread via the lungs.

And now... A striking metastudy published in late December 2021 looked at data from 81 research articles tracking fatigue and cognitive impairment in people at least 12 weeks after COVID-19. The findings revealed lingering fatigue in 32% of all COVID-19 patients at least three months after the acute disease, and signs of cognitive impairment in 22% of all patients.
Even more significantly, the research found no difference in the rate of fatigue and cognitive impairment between hospitalized and non-hospitalized populations. While other symptoms of long COVID did seem to correlate with initial disease severity, these two specific factors seemed to be persistent regardless of how mild the original case was.


So, it is postulated that the wider spread of Omicron will lead to a wider spread of long covid.
If the evolution of covid is towards less severe but more transmissible, this is not good news.
https://newatlas.com/health-wellbeing/long-covid-mild-infections-omicron-autoantibodies/

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swill453
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Re: Long covid

#471168

Postby swill453 » January 7th, 2022, 3:27 pm

It's probably far too early to be able to tell, but there have been indications that Omicron attacks the windpipe more than the lungs, when compared to other variants.

This may mean long covid is less of an issue from Omicron.

Scott.

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Antiviral Roll-out - letter from NHS with PCR

#471193

Postby Bouleversee » January 7th, 2022, 4:33 pm

Antiviral treatments are now available which are supposed to stop some of those who are on the clinically highly vulnerable list from getting seriously ill and the NHS has apparently written to those who are listed as being eligible telling them what to do if they develop Covid symptoms (unfortunately they are listing those produced by the Delta variant rather than the quite different ones normally produced by Omicron) and enclosing a PCR test with instructions as to what to do if positive. It tells people who think they are eligible but have not received any such letter by Jan. 10 to dial 119. I hope they amend the options before then as there isn't one that fits at the moment.

I was surprised to see that the list did not include any of the respiratory diseases which have previously been classed as highly vulnerable, requiring shielding, and wonder why. Maybe the last post on the Long Covid thread (above) might offer a clue; Swill said: "It's probably far too early to be able to tell, but there have been indications that Omicron attacks the windpipe more than the lungs, when compared to other variants." I was aware that Omicron didn't attack the lower lungs in the same way as previous variants, but I hadn't realised that it would not affect them at all and I am surprised that elderly people with such as COPD or IPF would not still be at as much risk of serious effects as, say, MS patients (who are on the eligible list) but there is obviously a lot I don't know about the new variant and how it affects people.

Has anyone had this NHS letter yet and does anyone know any more about how the list choices was arrived at? I had planned to ring 119 on Monday if my letter does not arrive by then but I don't want to make a fool of myself or waste their time or my own.
I tried my GP practice, my chest clinic (couldn't even get to speak to anyone there) and the two lung foundations but nobody could enlighten me. I'm not worried, just intellectually curious and I like things to make sense.

https://www.nhs.uk/conditions/coronavir ... ronavirus/

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Re: Long covid

#471200

Postby Julian » January 7th, 2022, 5:06 pm

swill453 wrote:It's probably far too early to be able to tell, but there have been indications that Omicron attacks the windpipe more than the lungs, when compared to other variants.

This may mean long covid is less of an issue from Omicron.

Scott.

I agree. Also (and maybe related) Omicron doesn’t seem to be triggering the same level of cell syncytia as previous variants did { page 13 of https://www.gla.ac.uk/media/Media_829360_smxx.pdf ] and there is speculation that syncytia is a factor in long Covid { https://www.drugtargetreview.com/news/7 ... cientists/ } so while I 100% agree with the “probably too early to … tell” comment there are, as well as the concerns about the pure number of infections potentially leading to more long Covid, also some hope that there might be other factors unique (for now) to Omicron that offset that “pure numbers” concern.

- Julian


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